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We create hope and build healthier futures. Children's Hospital Los Angeles is a nonprofit organization that depends on your generous donations to heal children in an environment that lets them thrive. Each year, more than 107,000 sick children come to the hospital for care. Support from the community helps pay for the breakthrough therapies and treatments that save young lives each year. As a leading academic children’s hospital, we fulfill our mission by: Caring for children, adolescents, young adults, families and each other, advancing knowledge, preparing future generations, and building our financial strength.

The Palestine Children's Relief Fund (PCRF) is a non-political, non-profit organization dedicated to healing the wounds of war, occupation and poverty for children in the Middle East, regardless of their nationality, religion, race or gender.

The mission of The University of Texas MD Anderson Cancer Center is to eliminate cancer in Texas, the nation and the world through outstanding programs that integrate patient care, research and prevention and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.

Blood Cancer United is a global leader in the fight against cancer. The Blood Cancer United mission: Cure leukemia, lymphoma, Hodgkin's disease and myeloma, and improve the quality of life of patients and their families. Blood Cancer United funds lifesaving blood cancer research around the world, provides free information and support services, and is the voice for all blood cancer patients seeking access to quality, affordable, coordinated care.

Established in 1985, The ALS Association is dedicated to leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support. The Association builds hope and enhances the quality of life while aggressively searching for new treatments and a cure, through global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships.

CAWC is committed to ending domestic violence. Using a self-help, empowerment approach, we provide counseling, advocacy, and a 24-hour hotline for people affected by domestic violence, including a shelter for women and children. We work for social change through education, service collaboration, and institutional advocacy.

Accelerating CF research to save lives through the power of community. Emily's Entourage raises money and awareness to help find a cure for Cystic Fibrosis (CF) with a focus on nonsense mutations. Nearly 70,000 people worldwide with CF are waiting with bated breath for life-saving breakthroughs. We're mobilizing friends, families, businesses and communities to join Emily's Entourage on our quest for new treatments and a cure.