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The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

Memorial Sloan-Kettering Cancer Center is dedicated to leading the fight against cancer, individually focusing on each patient and creating an impact on cancer treatment and the biomedical research agenda around the world. As one of the world's premier cancer centers, Memorial Sloan Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between its physicians and scientists is one of its unique strengths, enabling it to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future.

Our mission is a preferential option for the poor in health care. By establishing long-term relationships with sister organizations based in settings of poverty, Partners In Health strives to achieve two overarching goals: to bring benefits of modern medical science to those most in need of them and to serve as an antidote to despair. We draw on the resources of the world's leading medical and academic institutions and on the lived experience of the world's poorest and sickest communities. At its root, our mission is both medical and moral. It is based on solidarity, rather than charity alone. When our patients are ill and have no access to care, our team of health professionals, scholars, and activists will do whatever it takes to make them well- just as we would do if a member of our own families, or we ourselves, were ill.

Islamic Relief USA provides relief and development in a dignified manner regardless of gender, race, or religion, and works to empower individuals in their communities and give them a voice in the world. Our values are excellence, sincerity, social justice, compassion, and custodianship. For Islamic Relief, advocacy means working with you to elevate humanitarian voices and the voices of those we serve.

Samaritan's Purse is a nondenominational evangelical Christian organization providing spiritual and physical aid to hurting people around the world. Since 1970, Samaritan's Purse has helped meet needs of people who are victims of war, poverty, natural disasters, disease, and famine with the purpose of sharing Gods love through His son, Jesus Christ. The organization serves the church worldwide to promote the Gospel of the Lord Jesus Christ.

Heifer International's mission is to end hunger and poverty while caring for the Earth in a sustainable way by supporting and investing alongside local farmers and their communities. Since 1944, Heifer has helped transform more than 52 million households by working in partnership with the communities we serve. Our programs support entrepreneurs around the world, creating lasting change from the ground up. It begins with a seed investment of livestock or agriculture, followed by mentorship to help project participants build a business, and ultimately to gain access to supply chains and markets. These families are able to earn a living income and continuously lift up their communities as they train the next generation of leaders. By supporting and training the world's farmers, ranchers, and female business owners, we're investing in a new breed of success. Heifer International by the numbers: *Currently operating in 19 countries *Over 1M active participant households in Heifer programs *Over 9M people trained since 2012 *67% of Heifer program participants in 2024 were women

The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.

Wags and Walks is a community of dog lovers working to promote shelter dogs as the best dogs in the world through advocacy of our unique family-friendly foster and adoption programs. Wags and Walks is dedicated to rescuing family-friendly dogs from shelters and finding them suitable permanent homes. Working with committed volunteers, foster homes, veterinarians, and trainers, we are able to rescue hundreds of dogs every year and provide them with loving temporary care while finding them well-matched, carefully screened forever homes.

From the website: "Miriam's House is a sober living transitional home for women and their children. Miriam's House opened its doors in 2007 to better serve mothers in recovery. Our unique program allows for mothers to get the help they need while maintaining or recovering custody of their children. Our mission is to empower these families with the critical life skills needed for a substance-abuse free future. We fulfill our mission by providing the mothers and children with a safe and nurturing environment and comprehensive social services." Miriam's House was formerly known as Promises Foundation.

Covenant House provides a community of hope and healing to homeless young people in need of a safe haven. For kids who have run away from or been forced out of their family home or aged out of foster care, Covenant House provides a temporary home and a continuum of services designed to help them escape the streets forever and transition to a life with stable housing, a solid educational foundation, and sustained employment. . Founded in 1972, Covenant House has reached more than one million young people with immediate assistance and the support necessary to transition from a life on the streets to a life with a future.

DoSomething.org is mobilizing young people in every US area code and in 131 countries! We support causes in education, racial justice, gun violence, physical and mental health, bullying, gender rights, LGBTQ+ rights, discrimination, voter registration, environment, and many more. Sign up for a volunteer, social change, or civic action campaign to make real-world impact on a cause you care about. You’ll team up with the DoSomething members who have: Clothed half of America’s homeless youth Cleaned up 3.7 million cigarette butts Run the largest youth-led sports equipment drive And more! You’ve got the power and the passion to transform your community -- we’ll help you get it done.

St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.