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The core mission of the IRSF is to fund research for treatments and a cure for Rett syndrome while enhancing the overall quality of life for those living with Rett syndrome by providing information, programs, and services. In 1983, a small dedicated group of parents whose children had Rett syndrome formed the first non-profit to focus exclusively on Rett syndrome – International Rett Syndrome Association (IRSA). In 2007, IRSA and Rett Syndrome Research Foundation (RSRF) consolidated resources to better serve families and maximize research investments toward a cure. The International Rett Syndrome Foundation (IRSF) emerged with a mission to accelerate research and empower families that builds upon these foundations’ pioneering work toward care and cure. We are walking this journey with you. IRSF is comprised of parents and friends of those diagnosed with Rett syndrome. We are dedicated to empowering families with the latest medical information, offering meaningful support and resources, and advocating for all those living with Rett syndrome. Our strategy is simple but powerful: improve care today and create treatments for tomorrow. IRSF is committed to a full-spectrum approach, providing solutions for everyone living with Rett syndrome. We do this by investing in innovative research, working to build a robust treatment pipeline, and removing barriers to ensure clinical trial success.

Endangered Species International (ESI) is strongly committed to reversing the trend of human-induced species extinction, saving endangered animals, and preserving wild places! ESI uses less than 2% of its budget for management and operations. ESI won multiple Top-Rated Awards from GreatNonprofits and has reached the Platinum participation level through the GuideStar Exchange.

Open Door International is a nonprofit 501 (c) (3) corporation dedicated to providing recently returned missionaries (both service and teaching missionaries) for the Church of Jesus Christ of Latter-day Saints with opportunities for stable employment, continued education, and ongoing service in the Church and community. We do this by providing housing for missionaries in a location more central to employment and educational resources. While living in an Open Door home, we help returned missionaries plan and connect to these resources and opportunities.

We serve American children as their national arts organization, seeding their imagination, cultivating creativity, and fostering mutual empathy among them (for “a more perfect union”) and with their peers worldwide (for a peaceful future). Founded in 1997, the International Child Art Foundation (ICAF) organizes the Arts Olympiad, a school art program that has grown over the years into the world’s largest; it also produces the World Children’s Festival at the National Mall, located across from the U.S. Capitol. ICAF's ad-free ChildArt quarterly magazine enhances cross-cultural understanding and global competencies. ICAF has organized Healing Art Programs to revive faith in nature of child victims of natural disasters, and Peace through Art Programs to restore trust in humanity of children in conflict zones.

NEI’s mission is to establish a self-sustainable soybean industry in Afghanistan through developing a soybean full value chain; which includes seed multiplication, soybean cultivation, soybean processing, and soy market development.

Family Legacy is a faith-based, Christian, God-led organization that exists to glorify God by empowering vulnerable children in Zambia to live out their God-given potential. We do this by engaging more than 10,000 individuals and families from around the world with God’s heart for these children, face-to-face and heart-to-heart, through the power of God’s word, quality education and residential care.With almost 14,000 Zambian children attending one of our private Christian Legacy Academy schools, Family Legacy is not an orphanage or a missionary organization or an economic development organization. We are a unique NGO focused on caring for orphaned and vulnerable/at-risk Zambian children on a variety of levels.

Together, we create life-changing wishes for children with critical illnesses

"Our mission is to harness the power of every individual through education, training, and volunteer service."

For over 75 years, 1350 Squadron has been changing the lives of young people in Fareham. offering them opportunities for fun, new friends, new experiences and personal development. Cadets get involved in a huge range of new experiences, develop new skills and discover more about themselves.Cadets support each other in an inclusive atmosphere, enjoying activities that are organised and supervised by vetted and qualified adult volunteers.Cadets take responsibility for themselves and their kit, then those around them and their team, building experience of teamwork and becoming a leader.

Inspiring the next generation to realise their potential and seize a better future through nautical adventure based on the customs and traditions of the Royal Navy.

Providing amazing adventures for young people age 10-18. Transforming them into confident, resilient young people who thrive in a complex world, whatever they want to do when they leave school. Experience sailing, canoeing, adventure training, drill, discipline and life on board Naval training Ships

Our Mission: To help those who have served our country honorably live with dignity and independence. The service dog programs of America’s VetDogs® were created to provide enhanced mobility and renewed independence to veterans, active-duty service members, and first responders with disabilities, allowing them to once again live with pride and self-reliance. Not only does a service dog provide support with daily activities, it provides the motivation to tackle new challenges. VetDogs trains and places guide dogs for individuals who are blind or have low vision; PTSD service dogs to help mitigate the effects of post-traumatic stress disorder; hearing dogs for those who have lost their hearing later in life; service dogs for those with other physical disabilities, and facility dogs as part of the rehabilitation process in military and VA hospitals. It costs over $50,000 to breed, raise, train, and place one assistance dog; however, all of VetDogs’ services are provided at no charge to the individual. Funding comes from the generosity of individuals, corporations, foundations, businesses, and service and fraternal clubs. Once they make the decision to get a service dog, applicants become part of VetDogs’ open and welcoming community. They are supported with an uncompromised commitment to excellence, from highly empathetic and certified trainers to a meticulously constructed curriculum. VetDogs teams each student with the dog that’s right for them – and the power of their bond makes ordinary moments extraordinary. Crossing the street independently becomes a moment of liberation. Traveling alone becomes a welcome adventure. Embracing new experiences becomes an everyday occurrence. America’s VetDogs launched in 2003 as a project of the Guide Dog Foundation. In 2006, it became a separate 501(c)(3) corporation; the two organizations continue to share staff and other resources to ensure people with disabilities receive the best services possible. With an assistance dog from America's VetDogs by their side, a hero is never alone. With their courage and determination, these remarkable teams reconnect us all to the highest form of freedom there is: the freedom to experience the world around us in any way we choose, and to live without boundaries.