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The American Foundation for Suicide Prevention is dedicated to saving lives and bringing hope to those affected by suicide. AFSP creates a culture that’s smart about mental health through education and community programs, develops suicide prevention through research and advocacy, and provides support for those affected by suicide. AFSP has local chapters in all 50 states with programs and events nationwide.

Memorial Sloan-Kettering Cancer Center is dedicated to leading the fight against cancer, individually focusing on each patient and creating an impact on cancer treatment and the biomedical research agenda around the world. As one of the world's premier cancer centers, Memorial Sloan Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between its physicians and scientists is one of its unique strengths, enabling it to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future.

City of Hope, an innovative biomedical research, treatment and educational institution, is dedicated to the prevention and cure of cancer and other life-threatening diseases, guided by a compassionate, patient-centered philosophy and supported by a national foundation of humanitarian philanthropy. City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases. Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged. Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully. City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo: "There is no profit in curing the body, if, in the process, we destroy the soul."

The Foundation's goal is to provide the ultimate environment for a child to become their best in all areas of their life, including academic, athletic, interpersonal skills, leadership, as a mentor, and someone willing to be mentored. They hope to arm children with a variety of ways to grow intellectually, spiritually, physically, and in their relationships with themselves and others. Their program is designed to go deeper into the subjects of life, excellence, and how to pursue happiness. In the end, our long-term goal is to help them become professionals in life, to find peace of mind, so they can share this wisdom with their families, friends, and communities as leaders and examples of extraordinary living and happiness.

NAMI is the National Alliance on Mental Illness, the nation’s largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI advocates for access to services, treatment, supports and research and is steadfast in its commitment to raise awareness and build a community of hope for all of those in need. We value hope, inclusion, empowerment, compassion and fairness. NAMI envisions a world where all people affected by mental illness live healthy, fulfilling lives supported by a community that cares.

Direct Relief improves the health and lives of people affected by poverty or emergency situations by mobilizing and providing essential medical resources needed for their care. Direct Relief works in all 50 U.S. states and in more than 90 countries to expand access to medicine and healthcare by equipping doctors and nurses with lifesaving medical resources.

The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

The Cystic Fibrosis Foundation's mission is to find a cure for cystic fibrosis (CF) and to improve the quality of life for people living with the disease. We accomplish this by funding life-saving research and working to provide access to quality care and effective therapies for people with CF. Our work has contributed to doubling the life expectancy for people with CF beyond the age of 18, and increasing the availability of nearly every CF drug through the Foundation's support.

charity: water is a non-profit organization bringing clean and safe drinking water to people in developing nations. We inspire giving and empower others to fundraise for sustainable water solutions. We use local partners on the ground to build and implement the projects. Then, we prove every single project funded, using GPS coordinates, photos and stories from the field. We have funded 91, 414 water projects, aimed to serve 14, 762, 215 people in 29 countries. We believe that sustainable work is locally-led. Along with implementing community-owned water projects, our local partners help facilitate comprehensive water, sanitation, and hygiene (WASH) programming to protect everyone’s long-term health.

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

To improve the quality of life for all LGBTQ+ people in Upstate, South Carolina.