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JDRF's mission is to find a cure for type 1 diabetes and its complications through the support of research. It is also committed to developing new and better treatments that improve the lives of people with type 1 diabetes in the near term and keep them healthy while we advance toward a cure. JDRF’s promise is to progressively remove the impact of T1D from the lives of those living with the disease until it is no longer a threat to them or their families.

The Pancreatic Cancer Action Network (PanCAN) is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer. Our mission is to take bold action to improve the lives of everyone impacted by pancreatic cancer by advancing scientific research, building community, sharing knowledge, and advocating for patients. PanCAN has invested more than $149 million in research since 2003. In the past year our nationwide PurpleStride community raised $11.8 million to fund our critical research and programs and services for patients. We have more than 700 PanCAN volunteer leaders driving local community action in our nationwide moment.

charity: water is a non-profit organization bringing clean and safe drinking water to people in developing nations. We inspire giving and empower others to fundraise for sustainable water solutions. We use local partners on the ground to build and implement the projects. Then, we prove every single project funded, using GPS coordinates, photos and stories from the field. We have funded 91, 414 water projects, aimed to serve 14, 762, 215 people in 29 countries. We believe that sustainable work is locally-led. Along with implementing community-owned water projects, our local partners help facilitate comprehensive water, sanitation, and hygiene (WASH) programming to protect everyone’s long-term health.

Founded in 1947, Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases. As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations and disseminates innovative patient therapies and scientific discoveries in Boston, across the United States and throughout the world.

Our mission is to be a relentless force in building a world of strong, healthier lives, free of cardiovascular diseases and stroke. Our mission drives everything we do. We’re the nation’s leader in CPR education training. We help people understand the importance of healthy lifestyle choices. We provide science-based treatment guidelines to healthcare professionals to help ensure the best treatment for every patient, every time. We educate lawmakers, policy makers and the public as we advocate for changes to protect and improve the health of our communities.

To Write Love on Her Arms (TWLOHA) is a non-profit movement dedicated to presenting hope and finding help for people struggling with depression, addiction, self injury, and suicide. TWLOHA exists to encourage, inform, inspire, and invest directly into treatment and recovery. Among many of their impactful tools the “Find Help” tool offers 24-hour helplines for when immediate help is needed under the following specific categories: suicide, trauma, LGBTQIA+, veterans, eating disorders, depression + anxiety, self-injury and addiction. Through donations TWLOHA seeks to educate communities, provide hope and encouragement, and connect people to the help they deserve.

Mount Sinai is committed to the advancement of the art and science through clinical excellence the central mission consists of high-quality patient care and teaching conducted in an atmosphere of social concern and scholarly inquiry into nature, causation, prevention and treatment of human disease. Mount Sinai values safety, equity, agility, creativity, empathy, and teamwork. Our commitment to these values have led several hospitals within our system to receiving the Magnet designation from the American Nurses Credentialing Center, a prestigious award that represents a gold standard in nursing care. At Mount Sinai: We Find A Way.

Rebuilding Together is a national housing organization that envisions a safe and healthy home for every person. Together with over 140 affiliates throughout the country, we provide, at no cost to the homeowner, critical home repairs for low-income homeowners, including seniors, veterans, families with young children and victims of disaster. Over the past 30 years, we have successfully: engaged 3.99 million volunteers who have completed 191,955 repairs and rehabs for homes, nonprofit facilities and community spaces, which have collectively served over 5.7 million community members totaling a $1.86 billion reinvestment in communities across the country since our inception.

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future.

The American Kidney Fund fights kidney disease on all fronts as the nation's leading kidney nonprofit. We work on behalf of the 37 million Americans living with kidney disease, and the millions more at risk, with an unmatched scope of programs that support people wherever they are in their fight against kidney disease — from prevention through post-transplant living.

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.